A note on urine trans, trans muconic acid level among a sample of Thai police: implication for an occupational health issue.
نویسندگان
چکیده
Benzene exposure is of particular concern because recent research indicating that benzene exposure can result in chronic toxicity, therefore, monitoring for benzene exposure among at-risk workers is recommended. In exposure- and risk-evaluation, the monitoring of benzene by peripheral biomarker has several advantages over technical assessment of exposure. For this purpose, the urine trans, trans muconic acid (ttMA)e level is accepted as a useful monitoring tool for early diagnosis of dangerous exposure. Apart from the industrial workers, there are other occupations with high risk for benzene exposure. In this study, we study another at-risk occupation, the police. Thirty-nine urine samples were obtained from 39 Thai police working close to traffic in an urban area. All 39 samples were analyzed for ttMA level and compared to 10 other controls. The average urine ttMA level for the control and exposed group were < 0.05 mg/gCr and was 0.79 +/- 1.43 mg/gCr, respectively. Significant higher urine ttMA acid level among the police were observed (p <.05). Working in the air pollution in the urban area can be health hazard for the police. Exposure to the benzene from automobile exhaust can be an important occupational problem for these police.
منابع مشابه
Urinary Trans, Trans-Muconic Acid is Not a Reliable Biomarker for Low-level Environmental and Occupational Benzene Exposures
BACKGROUND Benzene is a known occupational and environmental pollutant. Its urinary metabolite trans, trans-muconic acid (tt-MA) has been introduced by some environmental and occupational health regulatory associations as a biological index for the assessment of benzene exposure; however, recently, doubts have been raised about the specificity of tt-MA for low-level benzene exposures. In the pr...
متن کامل[Assessment of urinary trans, trans-muconic acid as a biomarker of exposure to benzene].
OBJECTIVE To assess the use of trans, trans-muconic acid as a biomarker of occupational exposure to benzene. METHODS Trans, trans-muconic acid in urine samples of exposed (exposed group, n=36) and non-exposed (non-exposed group, n=116) workers to benzene. Urinary levels of trans, trans-muconic acid were quantified by high-performance liquid chromatography. The study sample consisted of subjec...
متن کاملبررسی میزان مواجهه با بنزن در کارگران پمپ بنزین از طریق ارزیابی محیطی و پایش شاخص زیستی
Background and objective: Benzene is one of the main pollutants in air and one of the most extensive chemical compound used in both natural and industrial processes. Benzene exposure leads to the most dangerous adverse health effects, particularly blood cancer. The aim of this study was to evaluate the gas station workers’ exposure to benzene by measuring benzene in breathing air and urinary tr...
متن کاملBiological monitoring of petrochemical industry workers exposed to benzene, toluene, xylenes, methyl ethyl ketone, and phenol in Southern Iran
Background: Volatile organic compounds (VOCs), including carcinogens and toxic compounds, are produced in petrochemical industries. We undertook this study in order to study workers’ respiratory exposure to different VOC concentrations and compare the results with the urinary levels of its metabolites and study the correlation between them in petrochemical industries. Materials and Met...
متن کاملUrine phenol levels among Thai police, implications for occupational health.
In this study, we study an at-risk occupation, the police. Forty-five urine samples were obtained from 45 Thai police working close to traffic in an urban area, for analysis of urine phenol levels. The average (mean +/- SD) urine phenol level in these police was 16.94 +/- 11.72 mg/g-Cr. Significantly higher urine phenol levels were found among police who had worked for longer durations (p < 0.05).
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ورودعنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 76 شماره
صفحات -
تاریخ انتشار 2003